产品名称：Anti-FRA1/FITC抗体

Anti-FRA1/FITC抗体

产品编号YB1154R-FITC

英文名称Anti-FRA1/FITC

中文名称FITC标记的FRA-1蛋白抗体

别    名Fos related antigen 1; FOS like antigen 1; FOS L1; FOSL 1; Fos related antigen 1; Fos-related antigen 1; FOSL1; FOSL1 protein; FOSL1_HUMAN; FRA 1; FRA-1.  

Anti-FRA1/FITC抗体

说 明 书100ul  

研究领域肿瘤  细胞生物  **学  转录调节因子  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应 Human, Mouse, Rat,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量30kDa

Anti-FRA1/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human FRA1

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-FRA1/FITC抗体

产品介绍background:

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq].

Subunit:

Heterodimer.

Subcellular Location:

Nucleus.

Similarity:

Belongs to the bZIP family. Fos subfamily.

Contains 1 bZIP (basic-leucine zipper) domain.

Anti-FRA1/FITC抗体Database links:

Entrez Gene: 8061 Human

Omim: 136515 Human

SwissProt: P15407 Human

Unigene: 283565 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

FOSL1蛋白对细胞因子、生长因子、感染或致癌刺激等生理或病理信号发生应答,调节基因的转录, 参与细胞的增殖、分化等过程. FOSL1在肿瘤形成及发展过程中, 通过促进细胞增殖、抑制分化、促进肿瘤细胞的侵袭和转移等过程发挥作