产品名称：Anti-APOE抗体

Cat. Number:

YB0167R

Quantity size:

0.1ml

Concentration:

Anti-APOE抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Anti-APOE抗体Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Anti-APOE抗体Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.
Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008].

Also known as:

Anti-APOE抗体Apolipoprotein E precursor; AD2; Alzheimer disease 2; Apo E; ApoE; APOEA; ApolipoproteinE; Apolipoprotein-E; Apoprotein; MGC1571; Apo E2; ApoE2; APOE 2; Apolipoprotein E2; LDLCQ5; LPG; APOE_HUMAN; Apo-E.

Specificity:

Storage:

Anti-APOE抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-APOE抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.yb010Ra01 结缔组织生长因子(CTGF)多克隆抗体 Polyclonal Antibody to Connective Tissue Growth Factor (CTGF) Rattus norvegicus (Rat)
yb010Rb51 结缔组织生长因子(CTGF)多克隆抗体 Polyclonal Antibody to Connective Tissue Growth Factor (CTGF) Oryctolagus cuniculus (Rabbit)
yb011Bo01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Bos taurus; Bovine (Cattle)
yb011Ca01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Canis familiaris; Canine (Dog)
yb011Eq01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Equus caballus; Equine (Horse)
yb011Ga01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Chicken (Gallus)
yb011Gu01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Cavia (Guinea pig )
yb011Hu01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Homo sapiens (Human)
yb011Mu01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Mus musculus (Mouse)
yb011Po01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Sus scrofa; Porcine (Pig)
yb011Ra01 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Rattus norvegicus (Rat)
yb011Rb52 脑源性神经营养因子(BDNF)多克隆抗体 Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF) Oryctolagus cuniculus (Rabbit)
yb012Bo01 S100钙结合蛋白(S100)多克隆抗体