产品名称：Anti-phospho-ATF2 (Thr69/71)抗体

Cat. Number:

YB3033R

Quantity size:

0.1ml

Concentration:

Anti-phospho-ATF2 (Thr69/71)抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Anti-phospho-ATF2 (Thr69/71)抗体ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.

Also known as:

Anti-phospho-ATF2 (Thr69/71)抗体ATF2 (phospho T69 + T71); ATF2 (phospho Thr69 + Thr71); p-ATF2 (T69 + T71); p-ATF2 (Thr69 + Thr71); CREB 2; HB 16;Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive; ATF2_HUMAN.

Specificity:

Storage:

Anti-phospho-ATF2 (Thr69/71)抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-phospho-ATF2 (Thr69/71)抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.yb793Mu01 S100钙结合蛋白A9(S100A9)多克隆抗体 Polyclonal Antibody to S100 Calcium Binding Protein A9 (S100A9) Mus musculus (Mouse)
yb794Hu01 成纤维细胞生长因子受体2(FGFR2)多克隆抗体 Polyclonal Antibody to Fibroblast Growth Factor Receptor 2 (FGFR2) Homo sapiens (Human)
yb795Hu01 血清淀粉样蛋白A2(SAA2)多克隆抗体 Polyclonal Antibody to Serum Amyloid A2 (SAA2) Homo sapiens (Human)
yb795Mu01 血清淀粉样蛋白A2(SAA2)多克隆抗体 Polyclonal Antibody to Serum Amyloid A2 (SAA2) Mus musculus (Mouse)
yb796Hu01 信号传导转录激活因子2(STAT2)多克隆抗体 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2) Homo sapiens (Human)
yb797Hu01 成纤维细胞生长因子受体3(FGFR3)多克隆抗体 Polyclonal Antibody to Fibroblast Growth Factor Receptor 3 (FGFR3) Homo sapiens (Human)
yb799Hu01 成纤维细胞生长因子受体4(FGFR4)多克隆抗体 Polyclonal Antibody to Fibroblast Growth Factor Receptor 4 (FGFR4) Homo sapiens (Human)
yb801Hu01 激肽释放酶原(PK)多克隆抗体 Polyclonal Antibody to Prekallikrein (PK) Homo sapiens (Human)
yb802Hu01 白介素32(IL32)多克隆抗体 Polyclonal Antibody to Interleukin 32 (IL32) Homo sapiens (Human)
yb807Hu01 Jagged 1蛋白(JAG1)多克隆抗体 Polyclonal Antibody to Jagged 1 Protein (JAG1) Homo sapiens (Human)
yb807Mu01 Jagged 1蛋白(JAG1)多克隆抗体 Polyclonal Antibody to Jagged 1 Protein (JAG1) Mus musculus (Mouse)
yb812Hu01 β-位淀粉样前体蛋白裂解酶2(βACE2)多克隆抗体 Polyclonal Antibody to Beta-Site APP Cleaving Enzyme 2 (bACE2) Homo sapiens (Human)
yb815Hu01 白介素6受体(IL6R)多克隆抗体 Polyclonal Antibody to Interleukin 6 Receptor (IL6R) Homo sapiens (Human)
yb815Mu01 白介素6受体(IL6R)多克隆抗体