产品名称：Anti-ADAM2抗体

Cat. Number:

YB5851R

Quantity size:

0.1ml

Concentration:

Anti-ADAM2抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ADAM-2, also known as PH-30?and Fertilin-? was first described as a sperm-egg fusion protein from guinea pig. A member of the metalloproteinase family containing disintigrin-like domains (ADAMs), the function of ADAM-2 is still poorly understood. Unlike ADAM-1, ADAM-2 does not contain the canonical HExxHxxxxxH zinc metalloproteinase motif, and is not thought to be proteolytically active. Like the other ADAMs, ADAM-2 domain structure consists of a signal sequence followed by a propeptide domain,Anti-ADAM2抗体 a metalloproteinase domain, a disintegrin domain cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic domain. Three isoforms of ADAM-2 are reported to date, which differ in the beginning of the metalloproteinase domain and cysteine-rich domain. The sequences are coded from intronless genes. The longest ADAM-2 message encodes a protein of 735 amino acids, with a predicted mass of 82.5 kDa and a pI of 5.73. The 716 amino acid form of ADAM-2 has a deletion in the start of the metalloproteinase domain, relative to the longer form, and has a predicted mass of 80.2 kDa and pI of 5.75. The shorter form of 579 amino acids shared the deletion in the MP domain, and also has a deletion in the cystein-rich domain. Localized on the surface of sperm, the ADAM-2 isoforms are thought to form a heterodimer with ADAM-1 (fertilin-a), and facilitate sperm-egg fusion, although there is some controversy about the precise actions the proteins play. Integrin a6? on the egg surface is thought to dock with a QDECD motif in the disintegrin domain of ADAM-2, and there is some speculation that ADAM-1/ADAM-2 heterodimewr initiated ADAM-3 production on the cell surface.

Also known as:

Anti-ADAM2抗体A disintegrin and metalloproteinase domain 2; ADAM 2; ADAM metallopeptidase domain 2; Adam2; ADAM2_HUMAN; AI323749; Cancer/testis antigen 15; CRYN1; CRYN2; CT15; Disintegrin and metalloproteinase domain-containing protein 2; Fertilin beta; Fertilin subunit beta; Ftnb; PH 30; PH 30b; PH-30; PH30; Ph30 beta; PH30-beta.

Specificity:

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-ADAM2抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.YB037Eq01 纤连蛋白(FN)多克隆抗体 Polyclonal Antibody to Fibronectin (FN) Equus caballus; Equine (Horse)
YB610Ge01 叶酸(FA)多克隆抗体 Polyclonal Antibody to Folic Acid (FA) General
YB759Ge01 赤霉素(GA)多克隆抗体 Polyclonal Antibody to Gibberellic Acid (GA) General
YB084Hu01 甘丙肽(GAL)多克隆抗体 Polyclonal Antibody to Galanin (GAL) Homo sapiens (Human)
YB084Mu01 甘丙肽(GAL)多克隆抗体 Polyclonal Antibody to Galanin (GAL) Mus musculus (Mouse)
YB084Ra01 甘丙肽(GAL)多克隆抗体 Polyclonal Antibody to Galanin (GAL) Rattus norvegicus (Rat)
YB900Ge01 γ-氨基丁酸(γABA)多克隆抗体 Polyclonal Antibody to Gamma-Aminobutyric Acid (gABA) General
YB506Hu01 胃泌素释放肽(GRP)多克隆抗体 Polyclonal Antibody to Gastrin Releasing Peptide (GRP) Homo sapiens (Human)
YB506Mu01 胃泌素释放肽(GRP)多克隆抗体 Polyclonal Antibody to Gastrin Releasing Peptide (GRP) Mus musculus (Mouse)
YB506Ra01 胃泌素释放肽(GRP)多克隆抗体 Polyclonal Antibody to Gastrin Releasing Peptide (GRP) Rattus norvegicus (Rat)
YB882Hu01 胃泌素抑制肽(GIP)多克隆抗体 Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP) Homo sapiens (Human)
YB882Mu01 胃泌素抑制肽(GIP)多克隆抗体 Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP) Mus musculus (Mouse)
YB882Ra01 胃泌素抑制肽(GIP)多克隆抗体 Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP) Rattus norvegicus (Rat)
YB224Hu01 胃泌素(GT)多克隆抗体 Polyclonal Antibody to Gastrin (GT) Homo sapiens (Human)
YB224Mu01 胃泌素(GT)多克隆抗体 Polyclonal Antibody to Gastrin (GT) Mus musculus (Mouse)
YB224Ra01 胃泌素(GT)多克隆抗体 Polyclonal Antibody to Gastrin (GT) Rattus norvegicus (Rat)
YB224Ca01 胃泌素(GT)多克隆抗体 Polyclonal Antibody to Gastrin (GT) Canis familiaris; Canine (Dog)
YB372Si01 凝溶胶蛋白(GS)多克隆抗体 Polyclonal Antibody to Gelsolin (GS) Rhesus monkey (Simian)
YB044Gu01 生长**(GH)多克隆抗体