产品名称：Anti-ANKRD17/FITC抗体

Anti-ANKRD17/FITC抗体

产品编号YB-9295R-FITC

英文名称Anti-ANKRD17/FITC

中文名称FITC标记的锚蛋白重复结构域蛋白17抗体

别    名ANKRD 17; ANKRD-17; Ankyrin repeat domain protein 17; Ankyrin repeat domain-containing protein 17; ANR17_HUMAN; FLJ22206; Gene trap ankyrin repeat; Gene trap ankyrin repeat protein; GTAR; KIAA0697; NY BR 16; Serologically defined breast cancer antigen NY-BR-16。

Anti-ANKRD17/FITC抗体

说 明 书100ul  

研究领域细胞生物  细胞周期蛋白  细胞分化  表观遗传学  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量274kDa

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human ANKRD17

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-ANKRD17/FITC抗体

产品介绍background:

ANKRD17 is a 2,603 amino acid protein that contains 25 ankyrin repeats and one KH domain. ANKRD17 is expressed in bone marrow and is thought to be involved in liver development. ANKRD17 localizes to the cytoplasm and the nucleus. ANKRD17 exists as five alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 4. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes.

Function:

Earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for characterization of inductive events involved in hepatic specification (By similarity). Anti-ANKRD17/FITC抗体Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease).

Subunit:

Interacts with VP1 capsid protein of enterovirus 71 (EV71).

Subcellular Location:

Cytoplasm. Nucleus. Detected around the nucleolus.

Tissue Specificity:

Anti-ANKRD17/FITC抗体Expressed in bone marrow.

Similarity:

Contains 25 ANK repeats.

Contains 1 KH domain.

Database links:

Entrez Gene: 9743 Human

Omim: 608541 Human

SwissProt: A7KAX9 Human

Unigene: 440379 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.