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Anti-Apoptosis enhancing nuclease/FITC抗体
产品编号YB-7604R-FITC
英文名称Anti-Apoptosis enhancing nuclease/FITC
中文名称FITC标记的细胞凋亡增强核酸酶抗体
别 名Aen; AEN_HUMAN; apoptosis enhancing nuclease; Apoptosis-enhancing nuclease; Interferon stimulated exonuclease gene 20kDa like 1; Interferon stimulated exonuclease gene 20kDa like 1, isoform CRA_a; Interferon-stimulated 20 kDa exonuclease-like 1; ISG20L1; pp12744.
Anti-Apoptosis enhancing nuclease/FITC抗体
说 明 书100ul
研究领域细胞生物 染色质和核信号 信号转导 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量36kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Apoptosis enhancing nuclease (31-55aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-Apoptosis enhancing nuclease/FITC抗体
产品介绍background:
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
Function:
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
Subcellular Location:
Nucleus. Nucleus, nucleolus. Note=Localized predomintly in the nucleolus. Anti-Apoptosis enhancing nuclease/FITC抗体Translocates from the nucleolus to the nucleoplasm upon apoptosis induction.
Anti-Apoptosis enhancing nuclease/FITC抗体Similarity:
Contains 1 exonuclease domain.
Database links:
UniProtKB/Swiss-Prot: Q8WTP8.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.