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Anti-AP2 gamma/FITC抗体
产品编号YB-6694R-FITC
英文名称Anti-AP2 gamma/FITC
中文名称FITC标记的转录因子AP-2γ抗体
别 名TFAP2C; AP2 γ; Activating enhancer binding protein 2 gamma; Activating enhancer-binding protein 2 gamma; AP2-gamma; AP2C_HUMAN; AP2g; AP2gamma; ERF 1; ERF1v; Estrogen receptor factor 1; hAP 2g; hAP2g; TFAP 2C; TFAP 2G; TFAP2C; TFAP2G; Transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma); Transcription factor AP 2 gamma; Transcription factor AP-2 gamma; Transcription factor AP2 gamma; Transcription factor ERF 1; Transcription factor ERF-1; Transcription factor ERF1.
Anti-AP2 gamma/FITC抗体
说 明 书100ul
研究领域细胞生物 信号转导 细胞周期蛋白 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Cow, Rabbit,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量49kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human TFAP2C (2-30aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-AP2 gamma/FITC抗体
产品介绍background:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Function:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Subunit:
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with KCTD1; Anti-AP2 gamma/FITC抗体this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the interaction stimulates TFAP2B-transcriptional activity.
Subcellular Location:
Nucleus.
Post-translational modifications:
Anti-AP2 gamma/FITC抗体Sumoylated on Lys-10; which inhibits transcriptional activity.
Similarity:
Belongs to the AP-2 family.
Database links:
UniProtKB/Swiss-Prot: Q92754.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.