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Anti-ADORA1/FITC抗体
产品编号YB6649R-FITC
英文名称Anti-ADORA1/FITC
中文名称FITC标记的腺苷A1受体抗体
别 名A1AR; A1R; AA1R; AA1R_HUMAN; Adenosine receptor A1; ADORA 1; ADORA1; RDC 7; RDC7; Ri.
Anti-ADORA1/FITC抗体
说 明 书100ul
研究领域心血管 细胞生物 神经生物学 信号转导 细胞凋亡 细胞膜受体 G蛋白偶联受体 G蛋白信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量37kDa
细胞定位细胞膜
Anti-ADORA1/FITC抗体性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Adenosine A1 Receptor
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
Anti-ADORA1/FITC抗体
产品介绍background:
Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway.
Function:
Receptor for adenosine.Anti-ADORA1/FITC抗体 The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:
UniProtKB/Swiss-Prot: P30542.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.