甲胎蛋白单克隆抗体
规格：1mg/1ml
英文名： AFP(A2)
别名： Alpha Fetoprotein; AFP; alpha 1 fetoprotein; alpha fetoglobulin; alpha Fetoprotein; Alpha fetoprotein precursor; FETA; HPAFP.
分子量： 65kDa
储存液：0.01M PBS(pH7.4) with 0.03% Proclin300.
克隆类型：Monoclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：Full length plasma AFP protein
交叉反应：Human,
甲胎蛋白单克隆抗体细胞定位：分泌型蛋白
产品介绍：background: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in *****s is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to甲胎蛋白单克隆抗体 screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries. Subunit: Dimeric and trimeric forms have been found in addition to the monomeric form. Subcellular Location: Secreted. Tissue Specificity: Plasma. Synthesized by the fetal liver and yolk sac. Similarity:甲胎蛋白单克隆抗体 Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains. Gene ID: 174 Database links: Entrez Gene: 174 Human Omim: 104150 Human SwissProt: P02771 Human Unigene: 518808 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. AFP是由胚胎卵黄囊细胞，胚胎肝细胞和胎儿肠道细胞合成的一种糖蛋白。主要用于原发性或转移性肝细胞癌、肝样胃癌和性腺或性腺外某些生殖细胞肿瘤(如内胚窦瘤)的诊断和鉴别诊断。 AFP敏感度较低，特异性强，大约60%左右的肝细胞肝癌阳性，在低分化肿瘤中常呈阳性表达。 该抗体与bsm-1622M（检测）（Anti-Alpha Fetoprotein）配对使用；主要用于ELISA试剂盒，胶体金试剂条制备生产都很好。大量订购可来电商议。
甲胎蛋白单克隆抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Mouse
外观： Lyophilized or Liquid