P物质抗体
规格：1mg/1ml
英文名： Substance P
别名： Hs.2563; Neurokinin 1; Neurokinin 2; Neurokinin A; Neurokinin alpha; Neuromedin L; Neuropeptide gamma; Neuropeptide K; NK2; NKA; NKNA; PPT; Protachykinin 1 precursor; Substance K; Substance P; TAC1; T
分子量： 1.4kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Substanc
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, G
P物质抗体细胞定位：分泌型蛋白
产品介绍：background: This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.P物质抗体 Subcellular Location: Secreted. Similarity: Belongs to the tachykinin family. Gene ID: 6863 Database links: Entrez Gene: 6863 Human Entrez Gene: 21333 Mouse Entrez Gene: 24806 Rat Omim: 162320 Human SwissProt: P20366 Human SwissProt: P41539 P物质抗体Mouse SwissProt: P06767 Rat Unigene: 2563 Human UniProtKB/Swiss-Prot: P20366.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. P物质（Substance P）是脑组织及消化道中发现的一种神经递质肽。由130个氨基酸残基组成，胃肠道中肌肉收缩的有力促进剂，亦为强血管扩张剂。 SP是一种脑肠肽，亦是*早发现的一种神经肽，属于速激肽家族成员，它广泛分布于**及外周神经系统，作为一种神经递质或调质参与疼痛、**、心血管等多种生理功能的调节。SP与其它的递质或调质类似，能作用于多种类型的受体，速激肽家族有NK1、NK2、NK3三种受体，都能与SP结合，其中NK1与SP的结合能力*强而被称为SP受体。
P物质抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid