神经营养因子抗体
规格：1mg/1ml
英文名： Neurturin
别名： Neurturin precursor; Neurturin; NRTN; NTN; NRTN_HUMAN.
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neurturi
交叉反应：Human, Mouse, Rat, Dog, Cow,
神经营养因子抗体细胞定位：分泌型蛋白
产品介绍：background: Human Neurturin (NTN) and Human GDNF comprise a family of TGF-beta related neurotrophic factor which have trophic influences on a variety of neuronal populations. Neurturin promotes the survival of certain sympathetic and sensory neurins through interaction with distinct set of GDNF-like receptors Function: Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. Subunit: Homodimer; 神经营养因子抗体disulfide-linked. Subcellular Location: Secreted. DISEASE: Note=Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. Similarity: Belongs to the TGF-beta family神经营养因子抗体. GDNF subfamily. Gene ID: 4902 Database links: Entrez Gene: 4902 Human Entrez Gene: 18188 Mouse Entrez Gene: 84423 Rat Omim: 602018 Human SwissProt: Q99748 Human SwissProt: P97463 Mouse Unigene: 234775 Human Unigene: 8074 Mouse Unigene: 21952 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经营养因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid