卷曲螺旋结构域蛋白18抗体
规格:1mg/1ml
英文名: CCDC18
别名: CCD18_HUMAN; Ccdc18; Coiled-coil domain-containing protein 18; Sarcoma antigen NY-SAR-24.
分子量: 169kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CCDC18
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,
细胞定位:
卷曲螺旋结构域蛋白18抗体产品介绍:background: CCDC18, also known as NY-SAR-41 or dJ717I23.1, is a 1,454 amino acid protein expressed as two isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in th卷曲螺旋结构域蛋白18抗体e nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. Database links: UniProtKB/Swiss-Prot: Q5T9S5.1 Important Note: This product as supplied is intended for research 卷曲螺旋结构域蛋白18抗体use only, not for use in human, therapeutic or diagnostic applications.
卷曲螺旋结构域蛋白18抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid