脑转录因子4蛋白抗体
规格：1mg/1ml
英文名： BRN4
别名： class 3; transcription factor 4; Brain specific homeobox POU domain protein 4; Brain-4; Brain-specific homeobox/POU domain protein 4; BRAIN4; Brn-4; BRN4; DFN3; Oct-9; Octamer-binding protein 9; Octam
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BRN4/POU
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
脑转录因子4蛋白抗体产品介绍：background: Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) . A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness. Function: Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain. Subcellular Location: Nucleus. Tissue Specificity: Brain specific. DISEASE: Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) [MIM:304400]. A mixed type of deafness characterized by both conductive hearing loss 脑转录因子4蛋白抗体resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness. Similarity: Belongs to the POU transcription factor family. Class-3 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. Gene ID: 5456 Database links: Entrez Gene: 5456 Human Entrez Gene: 18994 Mouse Entrez Gene: 29589 Rat Omim: 300039 Human SwissProt: 脑转录因子4蛋白抗体P49335 Human SwissProt: P62515 Mouse SwissProt: P62516 Rat Unigene: 2229 Human Unigene: 405149 Mouse Unigene: 56946 Mouse Unigene: 33030 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑转录因子4蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid