卵母细胞透明带糖蛋白2抗体
规格：1mg/1ml
英文名： Zona pellucida glycoprotein 2
别名： OTTHUMP; Processed zona pellucida sperm-binding protein 2; Zona pellucida glycoprotein 2; zona pellucida glycoprotein ZP2; Zona pellucida protein A; Zp-2; ZP2; ZP2_HUMAN; ZPA.
分子量： 78kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Zona pel
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, Bovine, Bos taurus
卵母细胞透明带糖蛋白2抗体细胞定位：细胞膜 分泌型蛋白
产品介绍：Function: The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. Subcellular Location: Secreted > extracellular space > extracellular matrix and Cell membrane. Tissue Specificity: Oocytes. Post-translational modifications: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. Additional proteolytically cleavage of the N-terminal peptide of 30 kDa occurs in one-cell and two-cell embryos (By similarity)卵母细胞透明带糖蛋白2抗体. Proteolytically cleaved in the N-terminal part probably by the metalloendopeptidase ASTL exocytosed from cortical granules after fertilization, yielding a N-terminal peptide of about 30 kDa which remains covalently attached to the C-terminal peptide via disulfide bond(s). This cleavage may play an important role in the post-fertilization block to polyspermy. -glycosylated; N-linked glycans are of high-mannose/hybrid type, as well as bi-, tri- and tetra-antennary sialylated complex types. O-glycosylated; contains sulfate-substituted glycans. Similarity: Polymers of 卵母细胞透明带糖蛋白2抗体ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers. Database links: Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卵母细胞透明带糖蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid