卷曲螺旋结构域蛋白22抗体
规格：1mg/1ml
英文名： CCDC22
别名： AI481216; CCD22_HUMAN; Ccdc22.
分子量： 71kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human CCDC22
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
卷曲螺旋结构域蛋白22抗体产品介绍：background: This gene encodes a protein containing a coiled-coil domain. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. Localization of the orthologous rat protein suggests that it may play a role in neuronal injury response. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2011]. Subunit: Interacts with CPNE1 and CPNE4 (By similarity). Tissue Specificity: Widely expressed in ***** tissues and in fetal liver and brain, with highest levels in prostate 卷曲螺旋结构域蛋白22抗体and lowest in skeletal muscle. DISEASE: Note=May be involved in X-linked syndromic mental retardation (PubMed:21826058). CCDC22 expression has been found to be down-regulated in a family with a phenotype consistent with X-linked syndromic mental retardation, and carrying variant Ala-17. In addition to intellectual disability, affected individuals have cardiac and skeletal abnormalities. Similarity: Belongs to the 卷曲螺旋结构域蛋白22抗体CCDC22 family. Database links: UniProtKB/Swiss-Prot: O60826.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卷曲螺旋结构域蛋白22抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid