卷曲螺旋结构域蛋白89抗体
规格：1mg/1ml
英文名： CCDC89
别名： Bc8 orange-interacting protein; BOIP; CCD89_HUMAN; Ccdc89; Coiled-coil domain-containing protein 89.
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCDC89
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞核 细胞浆
卷曲螺旋结构域蛋白89抗体产品介绍：background: CCDC89 is a 374 amino acid cytoplasmic and nuclear protein that interacts with HRT1 and belongs to the CCDC89 family. The gene that encodes CCDC89 consists of more than 2,000 bases and maps to human chromosome 11q14.1. Chromosome 11, which comprises approximately 4% of the human genome, is considered a gene and disease association-dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are卷曲螺旋结构域蛋白89抗体 caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Subunit: Interacts with HEY1. Subcellular Location: Cytoplasm. Nucleus. Note=Uniformly distributed within the cell, but becomes recruited to the nucleus upon binding to HEY1. Similarity: Belongs to the 卷曲螺旋结构域蛋白89抗体CCDC89 family. Gene ID: 220388 Database links: Entrez Gene: 220388 Human SwissProt: Q8N998 Human Unigene: 376241 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产卷曲螺旋结构域蛋白89抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid