血小板白细胞C激酶底物同源结构域M2抗体
规格：1mg/1ml
英文名： PLEKHM2
别名： PH domain containing family M member 2; Pleckstrin homology domain containing family M (with RUN domain) member 2; Pleckstrin homology domain containing family M member 2; PLEKHM 2; RP11 169K16.1; Sal
分子量： 113kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PLEKHM2
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse,
细胞定位：细胞浆
血小板白细胞C激酶底物同源结构域M2抗体产品介绍：background: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo. Function: May play a role 血小板白细胞C激酶底物同源结构域M2抗体in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation. Subunit: Interacts with KIF5B. Interacts with the S.typhimurium sifA protein; 血小板白细胞C激酶底物同源结构域M2抗体required for S.typhimurium infection. Subcellular Location: Cytoplasm. Similarity: Contains 1 PH domain. Contains 1 RUN domain. Database links: UniProtKB/Swiss-Prot: Q8IWE5.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血小板白细胞C激酶底物同源结构域M2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 **及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid