BTB-kelch蛋白家族10抗体
规格：1mg/1ml
英文名： KBTBD10
别名： cb52; fb24f05; fc15e07; Gm112; KBTBD10; Kel like protein 23; Kelch related protein 1; KRP1; MGC143407; Sarcosin; sbcb52; wufb24f05; wufc15e07; KBTBA_HUMAN.
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KBTBD10
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
BTB-kelch蛋白家族10抗体产品介绍：background: Sarcosin contains 1 BTB (POZ) domain and is required for pseudopod elongation in transformed cells. Sarcosin mRNA is up-regulated by less than two folds in the heart in human patients with HCM. Function: Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Subunit: Interacts with NRAP (By similarity). Part of a complex that contains CUL3, RBX1 and KBTBD10. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, pseudopodium. Cell projection,BTB-kelch蛋白家族10抗体 ruffle. Note=Predominantly cytoplasmic but can co-localize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia. Post-translational modifications: Ubiquitinated and probably targeted for proteasomeBTB-kelch蛋白家族10抗体-independent degradation. Similarity: Contains 1 BTB (POZ) domain. Contains 5 Kelch repeats. Database links: UniProtKB/Swiss-Prot: O60662.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
BTB-kelch蛋白家族10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 发育生物学 信号转导 细胞凋亡 转录调节因子 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid