铜代谢结构域蛋白7抗体
规格：1mg/1ml
英文名： COMMD7
别名： C20orf92; Chromosome 20 open reading frame 92; COMM domain containing 7; COMM domain containing protein 7; COMMD 7; dJ1085F17.3; FLJ14987; MGC33315; OTTHUMP; COMD7_HUMAN.
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human COMMD7
交叉反应：Human, Mouse, Rat, Dog, Pig,
细胞定位：
铜代谢结构域蛋白7抗体产品介绍：background: COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The prototype of this family, MURR1/COMMD1, suppresses NFkB by affecting the association of NF-kappaB with chromatin. COMMD7 (COMM domain-containing protein 7) interacts with COMMD1 via its COMM铜代谢结构域蛋白7抗体 domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity. Function: Associates with the NF-kappa-B complex and suppresses its transcriptional activity. Subunit: Interacts (via COMM domain) with COMMD1 铜代谢结构域蛋白7抗体(via COMM domain). Tissue Specificity: Widely expressed with highest expression in lung. Similarity: Contains 1 COMM domain. Database links: UniProtKB/Swiss-Prot: Q86VX2.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
铜代谢结构域蛋白7抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid