范可尼综合征相关锌指蛋白抗体
规格：1mg/1ml
英文名： TZFP/ZNF538
别名： FANCC interacting protein; FANCC-interacting protein; Fanconi anemia zinc finger protein; FAXF; FAZF; OTTHUMP; repressor of GATA; Rog; Testis zinc finger protein; ZBT32_HUMAN; Zbtb32; ZBTB3
分子量： 53kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TZFP/ZNF
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Cat,
细胞定位：细胞核
范可尼综合征相关锌指蛋白抗体产品介绍：Function: DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells. Subunit: Homodimer (via PTB domain). Interacts with the N-terminal of FANCC. Interacts with ZBTB16. Interacts with GATA3 (By similarity). Subcellular Location: Nucleus. Located in nuclear speckles. Tissue Specificity: Predominantly expressed in testis. Some isoforms are ubiquitously expressed. Similarity: Belongs to the krueppel 范可尼综合征相关锌指蛋白抗体C2H2-type zinc-finger protein family. Contains 1 BTB (POZ) domain. Contains 3 C2H2-type zinc fingers. Gene ID: 27033 Database links: Entrez Gene: 27033 Human Entrez Gene: 58206 Mouse Entrez Gene: 688845 Rat Omim: 605859 Human SwissProt: 范可尼综合征相关锌指蛋白抗体Q9Y2Y4 Human SwissProt: Q9JKD9 Mouse Unigene: 99430 Human Unigene: 116789 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
范可尼综合征相关锌指蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid