胶原蛋白和钙结合表皮生长因子结构域1抗体
规格：1mg/1ml
英文名： CCBE1
别名： CCBE 1; ccbe1; CCBE1_HUMAN; Collagen and calcium binding EGF domain containing protein 1; Collagen and calcium binding EGF domains 1; Collagen and calcium-binding EGF domain-containing protein 1; Full
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCBE1
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Zebrafish
细胞定位：分泌型蛋白
胶原蛋白和钙结合表皮生长因子结构域1抗体产品介绍：background: This gene is thought to function in extracellular matrixremodeling and migration. It is predominantly expressed in theovary, but down regulated in ovarian cancer cell lines and primarycarcinomas, suggesting its role as a tumour suppressor. Mutationsin this gene have been associated with Hennekamlymphangiectasia-lymphedema syndrome, a generalized lymphaticdysplasia in humans. [provided by RefSeq, Mar 2010]. Function: Required for lymphangioblast budding and angiogenicsprouting from venous endothelium during embryogenesis. Subcellular Location: Secreted (Potential). DISEASE: Defects in CCBE1胶原蛋白和钙结合表皮生长因子结构域1抗体 are the cause of Hennekamlymphangiectasia-lymphedema syndrome (HLLS) [MIM:235510]. HLLS is ageneralized lymph-vessels dysplasia characterized by intestinallymphangiectasia with severe lymphedema of the limbs, genitalia andface. In addition, affected individuals have unusual facies andsevere mental retardation. Similarity: Belongs to the CCBE1 family. Contains 1 EGF-like胶原蛋白和钙结合表皮生长因子结构域1抗体 domain. Database links: UniProtKB/Swiss-Prot: Q6UXH8.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胶原蛋白和钙结合表皮生长因子结构域1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid