粘附分子IgG样结构域蛋白3抗体
规格：1mg/1ml
英文名： AMIGO3
别名： Adhesion molecule with Ig like domain 3; ALI3; Alivin 3; AMIGO 3; Amphoterin induced gene and ORF 3; Amphoterin induced protein 3 precursor.AMGO3_HUMAN
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AMIGO3
交叉反应：Human, Pig, Rabbit,
细胞定位：细胞膜
粘附分子IgG样结构域蛋白3抗体产品介绍：background: The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin-3) plays a role in homophilic and/or粘附分子IgG样结构域蛋白3抗体 heterophilic cell-cell interaction and signal transduction. Function: AMIGO3 may mediate heterophilic cell-cell interaction and may also contribute to signal transduction through its intracellular domain. Subunit: Binds AMIGO1 or AMIGO2 (By similarity). Subcellular Location: Membrane; Single-pass type I membrane protein Similarity: Belongs to the immunoglobulin superfamily. AMIGO family. Contains 1 粘附分子IgG样结构域蛋白3抗体Ig-like C2-type (immunoglobulin-like) domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
粘附分子IgG样结构域蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid