锚蛋白重复结构域蛋白13A抗体
规格：1mg/1ml
英文名： ANKRD13A
别名： ANKRD13; ANKRD13A ankyrin repeat domain 13A; ANKRD13A; Ankyrin repeat domain 13; Protein KE03; AN13A_HUMAN.
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ANKRD13A
交叉反应：Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位：
锚蛋白重复结构域蛋白13A抗体产品介绍：Function: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. Subunit: Interacts (via the UIM 3 and 4 repeats) with EGFRc(ubiquitinated); the interaction is direct, inhibited by ANKRD13A monoubiquitination and may regulate EGFR internalization. Subcellular Location: Cell membrane.锚蛋白重复结构域蛋白13A抗体 Late endosome. Note=Interaction with EGFR may enhance association with the cell membrane. Post-translational modifications: Monoubiquitinated, inhibits interaction with ubiquitinated EGFR. Similarity: Contains 2 ANK repeats. Contains 3 UIM 锚蛋白重复结构域蛋白13A抗体(ubiquitin-interacting motif) repeats. Gene ID: 88455 Database links: Entrez Gene: 88455 Human Entrez Gene: 68420 Mouse SwissProt: Q8IZ07 Human SwissProt: Q80UP5 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锚蛋白重复结构域蛋白13A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid