砷酸盐耐药蛋白ARS2抗体
规格：1mg/1ml
英文名： ARS2
别名： ARS2 protein; Arsenate resistance protein ARS2; Arsenite resistance protein 2; Arsenite resistance protein; ASR2; MGC126427; Serrate; Serrate RNA effector molecule homolog (Arabidopsis); Serrate RNA e
分子量： 101kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ARS2 (72
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
砷酸盐耐药蛋白ARS2抗体细胞定位：细胞核 细胞浆
产品介绍：background: ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect 砷酸盐耐药蛋白ARS2抗体of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite. Subunit: Interacts with NCBP1 and DROSHA. Interacts with CASP8AP2 and ERBB4.砷酸盐耐药蛋白ARS2抗体Subcellular Location: Nucleus. Cytoplasm. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the ARS2 family. Database links: UniProtKB/Swiss-Prot: Q9BXP5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
砷酸盐耐药蛋白ARS2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid