水解酶结构域蛋白13抗体
规格：1mg/1ml
英文名： ABHD13
别名： ABHD13; ABHDD_HUMAN; abhydrolase domain containing 13; Abhydrolase domain-containing protein 13; BEM46L1; C13orf6.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ABHD13
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位：细胞膜
水解酶结构域蛋白13抗体产品介绍：background: The alpha/beta hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical alpha/beta hydrolase fold, which consists of an eightstranded parallel alpha/beta structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer’s disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members. Most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in 水解酶结构域蛋白13抗体an alternative synthesis pathway of NAE. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD13 is a 337 amino acid single-pass membrane protein that belongs to the ABHD family. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Similarity: Belongs to the serine esterase family. Database links水解酶结构域蛋白13抗体: Entrez Gene: 84945 Human Entrez Gene: 68904 Mouse Entrez Gene: 306630 Rat Entrez Gene: 561333 Zebrafish SwissProt: Q7L211 Human SwissProt: Q80UX8 Mouse SwissProt: Q32LS6 Zebrafish Unigene: 183528 Human Unigene: 142570 Mouse Unigene: 395885 Mouse Unigene: 88157 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
水解酶结构域蛋白13抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid