肿瘤/睾丸抗原44抗体
规格:1mg/1ml
英文名: TPTE
别名: Cancer/testis antigen 44; CT44; EC=3.1.3.48; HGNC:12023; PTEN2; Putative tyrosine protein phosphatase; Putative tyrosine-protein phosphatase TPTE; TPTE; TPTE_HUMAN; Transmembrane phosphatase with tens
分子量: 64kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TPTE
交叉反应:Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位:细胞膜
肿瘤/睾丸抗原44抗体产品介绍:background: TPTE is a 551 amino acid multi-pass membrane protein belonging to the PTEN-related family that is exclusively expressed in the testis and localizes to the plasma membrane in humans. The gene encoding TPTE is present in multiple copies in the human genome, some of which may be pseudogenes. TPTE contains one C2 tensin-type domain and one phosphatase tensin-type domain but, in humans, it does not exhibit phosphatase activity. However, the mouse ortholog (PTEN2) is a functional 3-phosphoinositide phosphatase that localizes to the Golgi apparatus and plays a possible role in signal transduction. In humans, four isoforms, namely肿瘤/睾丸抗原44抗体 TPTEå, TPTE∫, TPTE© and TPTE∂, are produced by alternative splicing of this gene. Function: Could be involved in signal transduction. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Exclusively expressed in testis. Similarity: Contains 1 C2 tensin-type domain. Contains 1 phosphatase tensin-type domain. Database links: Entrez Gene: 7179 Human Omim: 604336 Human SwissProt: 肿瘤/睾丸抗原44抗体P56180 Human Unigene: 122986 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤/睾丸抗原44抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞周期蛋白 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid