信号诱导增殖相关蛋白1样蛋白2抗体
规格:1mg/1ml
英文名: SIPA1L2
别名: SI1L2_HUMAN; Signal induced proliferation associated 1 like protein 2; Signal-induced proliferation-associated 1-like protein 2; SIPA1 like protein 2; SIPA1-like protein 2; SIPA1L2; SPAL2; KIAA1389.
分子量: 190kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SIPA1L2
交叉反应:Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位:
信号诱导增殖相关蛋白1样蛋白2抗体产品介绍:background: SIPA1L2 is a 1,722 amino acid protein that contains one PDZ (DHR) domain and one Rap-GAP domain, and exists as two alternatively spliced isoforms. The gene that encodes SPA-L2 consists of approximately 163,594 bases and maps to human chromosome 1q42.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is信号诱导增殖相关蛋白1样蛋白2抗体 associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Similarity: 信号诱导增殖相关蛋白1样蛋白2抗体Contains 1 PDZ (DHR) domain. Contains 1 Rap-GAP domain. Database links: Entrez Gene: 57568 Human Entrez Gene: 361442 Rat Omim: 611609 Human SwissProt: Q9P2F8 Human SwissProt: Q80TE4 Mouse SwissProt: Q5JCS6 Rat Unigene: 268774 Human Unigene: 271668 Mouse Unigene: 463243 Mouse Unigene: 44190 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
信号诱导增殖相关蛋白1样蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞周期蛋白 细胞分化 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid