CD20样蛋白抗体
规格:1mg/1ml
英文名: CD20L/MS4A3
别名: CD20 antigen homolog; CD20 antigen like; CD20 antigen like protein; CD20 antigen-like protein; CD20L; hematopoietic cell 4 transmembrane protein; Hematopoietic-specific transmembrane protein 4; HTm4;
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MS4A3/CD
交叉反应:Human,
细胞定位:细胞浆 细胞膜
CD20样蛋白抗体产品介绍:background: MS4A3 is a member of the membrane-spanning 4A gene family and displays unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A3 is likely to play a role in signal transduction and may function as a subunit associated with receptor complexes. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. Function: Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP). Subunit: Interacts with CDKN3. Interacts with CDKN3-CDK2 complexes through its binding to CDKN3; this interaction facilitates dissociation of cyclin A from CDKN3-CDK2 complexes. CD20样蛋白抗体Subcellular Location: Endomembrane system; Multi-pass membrane protein (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Located in the perinuclear area. Tissue Specificity: Expressed specifically in hematopoietic cells and tissues. Similarity: Belongs CD20样蛋白抗体to the MS4A family. Database links: Entrez Gene: 932 Human Omim: 606498 Human SwissProt: Q96HJ5 Human Unigene: 99960 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD20样蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-300 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 干细胞 细胞周期蛋白 激酶和磷酸酶 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid