ZBTB7C抗体

ZBTB7C抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产品具有以下特点:

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产品编号xy-13583R

英文名称ZBTB7C

中文名称锌指蛋白ZBTB7C抗体

别    名APM 1; APM1; B230208J24Rik; FLJ37907; ZBTB36; Zinc finger and BTB domain containing 7C.  

说 明 书100ul  200ul

研究领域转录调节因子  锌指蛋白  表观遗传学  

抗体来源Rabbit

克隆类型Polyclonal

ZBTB7C抗体交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量69kDa

细胞定位细胞核

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human ZBTB7C

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产品介绍background:

The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Zinc finger and BTB domain-containing protein 7C (ZBTB7C), also designated affected by papillomavirus DNA integration in ME180 cells protein 1 (APM-1), contains 1 BTB (POZ) domain and 4 C2H2-type zinc fingers. ZBTB7C is detected in normal cervical keratinocytes and may be a potential tumor suppressor gene against human papillomavirus (HPV) mediated cervical carcinogenesis.

Function:

The function of Anti-ZBTB7C has not yet been determined.

Tissue Specificity:

Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines.

Similarity:

Contains 1 BTB (POZ) domain.

Contains 4 C2H2-type zinc fingers.

SWISS:

A1YPR0

Gene ID:

201501