VPS36抗体

VPS36抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产品具有以下特点:

1、全：网络全世界的上等产品，基本上各种抗体产品在该公司均能找到

2、新：产品及网站更新非常快，基本上每周均有新产品出现

3、优：产品质量好，投诉比较少

4、强：强大的技术支持队伍和力量，网站上有齐全的技术资料以及客户评论，并提供实时在线技术咨询，使您使用产品时没有任何后顾之忧。

产品编号xy-12773R

英文名称VPS36

中文名称液泡蛋白分选蛋白36抗体

别    名C13orf9; CGI 145; EAP45; ELL associated protein of 45 kDa; ELL-associated protein of 45 kDa; ESCRT-II complex subunit VPS36; Vacuolar protein sorting associated protein 36; Vacuolar protein-sorting-associated protein 36; Vps36; VPS36_HUMAN.  

说 明 书100ul  200ul

研究领域细胞生物  信号转导  泛素  

抗体来源Rabbit

克隆类型Polyclonal

VPS36抗体交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量44kDa

细胞定位细胞核 细胞浆 细胞膜

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human VPS36

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产品介绍background:

This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A similar protein complex in rat is associated with RNA polymerase elongation factor II. [provided by RefSeq, Aug 2013]

Function:

Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.

Subcellular Location:

Cytoplasm. Endosome. Late endosome. Membrane. Nucleus. Colocalizes with ubiquitinated proteins on late endosomes. Recruited to the endosome membrane to participate in vesicle formation.

Similarity:

Belongs to the VPS36 family.

Contains 1 GLUE domain.

Gene ID:

51028