VILIP1抗体

VILIP1抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产品具有以下特点:

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产品编号xy-6118R

英文名称VILIP1

中文名称神经视锥蛋白样1抗体(神经钙蛋白)

别    名VILIP-1; 21 kDa CABP; Hippocalcin like protein 3; HLP 3; HLP3; HPCAL 3; HPCAL3; HUVISL1; Neural visinin-like protein 1; Neural visinin-like type 1 protein; Neurocalcin alpha; NVL 1; NVL1; Nvp1; OZ1; Ratnvp1; VILIP; Visinin; Visinin like 1; Visinin like protein 1; VISL 1; VISL1; Vnsl1; VISL1_HUMAN.  

说 明 书100ul  200ul

研究领域肿瘤  细胞生物  神经生物学  信号转导  结合蛋白  Alzheimer's  

抗体来源Rabbit

克隆类型Polyclonal

VILIP1抗体交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量22kDa

细胞定位细胞浆

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human VILIP1

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产品介绍background:

This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Function:

Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

Tissue Specificity:

Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).

Similarity:

Belongs to the recoverin family.

Contains 4 EF-hand domains.

Gene ID:

7447