TSPAN13抗体

TSPAN13抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产品具有以下特点:

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产品编号xy-9421R

英文名称TSPAN13

中文名称四分子交联体13抗体（四旋蛋白）

别    名NET 6; NET6; Tetraspan NET-6; Tetraspanin-13; TM4SF13; Transmembrane 4 superfamily member 13; Transmembrane 4 superfamily member tetraspan NET 6; Tspan-13; Tspan13; TSN13_HUMAN.  

说 明 书100ul  200ul

研究领域肿瘤  细胞生物  信号转导  通道蛋白  细胞分化  

抗体来源Rabbit

克隆类型Polyclonal

TSPAN13抗体交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用ELISA=1:500-1000 IHC-F=1:400-800 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量22kDa

细胞定位细胞膜

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human TSPAN13/NET-6

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产品介绍background:

NET-6, also known as TSPAN13 (tetraspanin-13) or TM4SF13 (transmembrane 4 superfamily member 13), is a 204 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission. The gene encoding NET-6 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Subcellular Location:

Membrane; Multi-pass membrane protein (Probable).

Similarity:

Belongs to the tetraspanin (TM4SF) family.

Gene ID:

27075