TIMM50抗体

TIMM50抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产品具有以下特点:

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产品编号xy-19932R

英文名称TIMM50

中文名称线粒体内膜转位同源蛋白50抗体

别    名Homolog of yeast Tim50; Import inner membrane translocase subunit TIM 50; Import inner membrane translocase subunit TIM50; Import inner membrane translocase subunit TIM50 mitochondrial; MGC102733; Mitochondrial import inner membrane translocase subunit TIM50; TIM 50; TIM 50L; TIM50; Tim50 like protein; TIM50_HUMAN; TIM50L; TIMM 50; TIMM50; Translocase of inner mitochondrial membrane 50 homolog (yeast); Translocase of inner mitochondrial membrane 50 homolog.  

说 明 书100ul  200ul

研究领域细胞生物  信号转导  转运蛋白  

抗体来源Rabbit

克隆类型Polyclonal

TIMM50抗体交叉反应 Human, Mouse, Rat,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量35kDa

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human TIMM50

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产品介绍Function:

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.

Subunit:

Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50; within this complex, directly interacts with TIMM23. The complex interacts with the TIMM44 component of the PAM complex and with DNAJC15.

Subcellular Location:

Mitochondrion inner membrane and Nucleus speckle. Nuclear and enriched in speckles with snRNPs.

Tissue Specificity:

Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level).

Similarity:

Belongs to the TIM50 family.

Contains 1 FCP1 homology domain.

SWISS:

Q3ZCQ8

Gene ID:

92609