产品详情
查看大图

  • 产品名称：GPSM2, Blocking Peptide

  • 产品型号：
  • 产品厂商：
  • 产品价格：0
  • 折扣价格：0
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
GPSM2, Blocking Peptide
详情介绍：
Product Name

GPSM2, Blocking Peptide

Full Product Name

GPSM2 Peptide - N-terminal region

Product Gene Name

GPSM2 blocking peptide

[Similar Products]
Product Synonym Gene Name
LGN; Pins; PINS; DFNB82[Similar Products]
Antibody/Peptide Pairs
GPSM2 peptide (MBS3235254) is used for blocking the activity of GPSM2 antibody (MBS3210298)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
TOP
OMIM
phenotype 609245
3D Structure
ModBase 3D Structure for P81274
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of GPSM2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
TOP
Related Product Information for
GPSM2 blocking peptide
This is a synthetic peptide designed for use in combination with anti-GPSM2 antibody made

Target Description: Heterotrimeric G proteins transduce extracellular signals received by cell surface receptors into integrated cellular responses. GPSM2 belongs to a group of proteins that modulate activation of G proteins.Heterotrimeric G proteins transduce extracellular signals received by cell surface receptors into integrated cellular responses. GPSM2 belongs to a group of proteins that modulate activation of G proteins (Blumer et al., 2002 [PubMed 11832491]).[supplied by OMIM].
Product Categories/Family for GPSM2 blocking peptide
Peptide
Applications Tested/Suitable for GPSM2 blocking peptide
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
TOP
NCBI/Uniprot data below describe general gene information for GPSM2. It may not necessarily be applicable to this product.
NCBI GI #
164519122
NCBI GeneID
29899
NCBI Accession #
NP_037428 [Other Products]
NCBI GenBank Nucleotide #
NM_013296 [Other Products]
UniProt Primary Accession #
P81274 [Other Products]
UniProt Related Accession #
P81274[Other Products]
Molecular Weight
76kDa
TOP
NCBI Official Full Name
G-protein-signaling modulator 2
NCBI Official Synonym Full Names
G protein signaling modulator 2
NCBI Official Symbol
GPSM2  [Similar Products]
NCBI Official Synonym Symbols
LGN; CMCS; PINS; DFNB82
  [Similar Products]
NCBI Protein Information
G-protein-signaling modulator 2
UniProt Protein Name
G-protein-signaling modulator 2
UniProt Synonym Protein Names
Mosaic protein LGN
Protein Family
G-protein-signaling modulator
UniProt Gene Name
GPSM2  [Similar Products]
UniProt Synonym Gene Names
LGN  [Similar Products]
UniProt Entry Name
GPSM2_HUMAN
TOP
NCBI Summary for GPSM2
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
TOP
UniProt Comments for GPSM2
GPSM2: Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. Interacts with LLGL2. Interacts with INSC/inscuteable and probably with F2RL2. Ubiquitously expressed. Belongs to the GPSM family.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: apical part of cell; cytoplasm; cell cortex

Molecular Function: identical protein binding; protein binding; GTPase regulator activity

Biological Process: G-protein coupled receptor protein signaling pathway; establishment of mitotic spindle orientation; regulation of catalytic activity

Disease: Chudley-mccullough Syndrome
Research Articles on GPSM2
1. The results show how E-cadherin instructs the assembly of the LGN/NuMA complex at cell-cell contacts, and define a mechanism that couples cell division orientation to intercellular adhesion.
TOP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
TOP
TOP
标题：
内容：
联系人：
联系电话：
Email：
公司名称：
联系地址：
 
 
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关文章

沪公网安备 31011202007343号