产品详情
简单介绍：
mMYC Purified Protein
详情介绍：
| Print Version | |
| Organism | Mouse |
| Accession # | P01108 |
| Alias | c-Myc |
| Protein Type | Wild Type |
| Protein Sequence | MPLNVNFTNRNYDLDYDSVQPYFICDEEENFYHQQQQSELQPPAPSEDIWKKFELLPAPPLSPSRRSGLCSPSYVAVATSFSPREDDDGGGGNFSTADQLEMMTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSTSLSPARGHSVCSTSSLYLQDLTAAASECIDPSVVFPYPLNDSSSPKSCTSSDSTAFSPSSDSLLSSESSPRASPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQTPAKRSESGSSPSRGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCSSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSIQADEHKLTSEKDLLRKRREQLKHKLEQLRNSGA |
| Protein Family | Not Specified. |
| Functions | Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. Myc is one of the four factors in the Yamanaka protocol for iPSC reprogramming. The recombinant protein within the lysate has a 6X His tag at N-terminus for purification and 9X Arginine at C-terminus for cell membrane penetration. |
| Cell Types | Expressed in the proliferating cells of the developing CNS and the epidermis. |
| Protein Location | Nucleus. |
| Tag | 6X His tag at N-terminus and 9X Poly-Arginine at C-terminus |
| Form | Liquid |
| Expression System | E.coli |
| Type | Purified Protein |
| Purification | Affinity Chromatography |
| Quality Control | By Western Blot Analysis |
| Concentration | 250ug/ml |
| Storage | PBS |
| Shipping | On dry ice. |
| Notes | For Research Use Only, not for therapeutic or diagnostic purposes. |
| References | Induction of pluripotent stem cells from ***** human fibroblasts by defined factors. Takahashi et al. Cell. 2007 Nov 30;131(5):861-72. Induction of pluripotent stem cells from mouse embryonic and ***** fibroblast cultures by defined factors. Takahaski and Yamanaka. Cell. 2006 Aug 25;126(4):663-76. Epub 2006 Aug 10. |
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