FITC - anti Mouse NK-1.1 - PEK136
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58,00 € tax excl.
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81,00 € tax excl.
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159,00 € tax excl.
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Product Description
- PEK136
- Mouse IgG2a
- Flow Cytometry
- FITC
- 0.5 mg/ml
- Mouse NK-1+ Spleen and Bone Marrow Cells
- Mouse
- The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
- RUO
- NK1.1, clone PEK136, is a mAb intended for RUO in the identification/enumeration of lymph that express NK1.1. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
- Liquid
- Store in the dark at 2-8 °C
NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-? production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
- NKR-P1C, NKR-P1B, Ly-55, CD161b, CD161c
- 17059
- 25 kD