产品详情
查看大图

  • 产品名称：TUBB2B, Polyclonal Antibody

  • 产品型号：
  • 产品厂商：
  • 产品价格：0
  • 折扣价格：0
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
TUBB2B, Polyclonal Antibody
详情介绍：
Product Name

TUBB2B, Polyclonal Antibody

Full Product Name

TUBB2B Antibody (N-term)

Product Synonym Names
Tubulin beta-2B chain; TUBB2B
Product Gene Name

anti-TUBB2B antibody

[Similar Products]
Antibody/Peptide Pairs
TUBB2B peptide (MBS9218739) is used for blocking the activity of TUBB2B antibody (MBS9202349)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
TOP
Immunogen Sequence Positions
12-39
OMIM
610031
3D Structure
ModBase 3D Structure for Q9BVA1
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human (Predicted Reactivity: Chicken, Monkey, Mouse, Rat, Bovine, Xenopus, Pig)
Specificity
This TUBB2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human TUBB2B.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-TUBB2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
TOP
Related Product Information for
anti-TUBB2B antibody
The protein encoded by this gene is a beta isoform of
tubulin, which binds GTP and is a major component of microtubules.
This gene is highly similar to TUBB2A and TUBB2C. Defects in this
gene are a cause of asymmetric polymicrogyria. [provided by
RefSeq].
Product Categories/Family for anti-TUBB2B antibody
Signal Transduction
Applications Tested/Suitable for anti-TUBB2B antibody
Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TUBB2B antibody
IF~~1:10~50
WB~~1:1000
Immunofluorescence (IF) of anti-TUBB2B antibody
Confocal immunofluorescent analysis of TUBB2B Antibody (N-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
anti-TUBB2B antibody Immunofluorescence (IF) image
Western Blot (WB) of anti-TUBB2B antibody
TUBB2B Antibody (N-term) western blot analysis in HepG2,Hela,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TUBB2B antibody detected the TUBB2B protein (arrow).
anti-TUBB2B antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-TUBB2B antibody
TUBB2B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TUBB2B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-TUBB2B antibody Immunohistochemistry (IHC) (IHC) image
TOP
NCBI/Uniprot data below describe general gene information for TUBB2B. It may not necessarily be applicable to this product.
NCBI GI #
29788768
NCBI GeneID
347733
NCBI Accession #
NP_821080.1 [Other Products]
NCBI GenBank Nucleotide #
NM_178012.4 [Other Products]
UniProt Primary Accession #
Q9BVA1 [Other Products]
UniProt Secondary Accession #
A8K068[Other Products]
UniProt Related Accession #
Q9BVA1[Other Products]
Molecular Weight
49953
TOP
NCBI Official Full Name
tubulin beta-2B chain
NCBI Official Synonym Full Names
tubulin, beta 2B class IIb
NCBI Official Symbol
TUBB2B  [Similar Products]
NCBI Official Synonym Symbols
PMGYSA; bA506K6.1
  [Similar Products]
NCBI Protein Information
tubulin beta-2B chain
UniProt Protein Name
Tubulin beta-2B chain
Protein Family
Tubulin
UniProt Gene Name
TUBB2B  [Similar Products]
UniProt Entry Name
TBB2B_HUMAN
TOP
NCBI Summary for TUBB2B
The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]
TOP
UniProt Comments for TUBB2B
TUBB2B: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2B is implicated in neuronal migration. Defects in TUBB2B are a cause of polymicrogyria asymmetric (PMGA). PMGA is a malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination. Belongs to the tubulin family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: microtubule; cytoplasm; nucleus

Molecular Function: GTPase activity; protein binding; GTP binding; structural constituent of cytoskeleton

Biological Process: protein polymerization; 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; neuron migration; transmembrane transport; microtubule-based process

Disease: Polymicrogyria, Symmetric Or Asymmetric
Product References and Citations for anti-TUBB2B antibody
Xu, W., et al. Mol. Cancer Ther. 8(12):3318-3330(2009)
Jaglin, X.H., et al. Nat. Genet. 41(6):746-752(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Cucchiarelli, V., et al. Cell Motil. Cytoskeleton 65(8):675-685(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Research Articles on TUBB2B
1. The association of polymicrogyria with thin or absent corpus callosum, dysmorphic basal ganglia, brainstem and vermis hypoplasia is highly likely to result from mutations in TUBB2B.
TOP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
TOP
TOP
标题：
内容：
联系人：
联系电话：
Email：
公司名称：
联系地址：
 
 
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关文章

沪公网安备 31011202007343号