名称：重组人ECH1/Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase/mitochondrialProtein（N-6His）；
产品说明(Description) Recombinant Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial is produced by our E.coli expression system and the target gene encoding Thr34-Leu328 is expressed with a 6His tag at the N-terminus. Accession #: Q13011 Known as: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase; mitochondrial;ECH1; 制剂（Formulation） Supplied as a 0.2 μm filtered solution of 20mM Tris,100mM NaCl,10% Glycerol,pH 8.0. 质量控制（Quality Control） Purity: Greater than 95% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. 复溶（Reconstitution） 保存（Storage） Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. 背景（Background） Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway. 电泳(SDS-PAGE) FOR RESEARCH USE ONLY