名称:重组小鼠Galectin-9/LGALS9Protein(N-GST);
产品说明(Description) Recombinant Mouse Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus. Accession #: O08573-2 Known as: Galectin-9; Lgals9; Gal-9 制剂(Formulation) Supplied as a 0.2 μm filtered solution of 1M PBS, 15% glycerol,pH8.0. 质量控制(Quality Control) Purity: Greater than 90% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. 复溶(Reconstitution) 保存(Storage) Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. 背景(Background) Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1. 电泳(SDS-PAGE) FOR RESEARCH USE ONLY