名称：重组小鼠Granzyme B(G,H)/GZMBProtein（C-6His）；
产品说明(Description) Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus. Accession #: P04187 Known as: Granzyme B(G;H);CTLA-1;Cytotoxic cell protease 1;CCP1;Fragmentin-2;Gzmb;Ctla-1; Ctla1 制剂（Formulation） Supplied as a 0.2 μm filtered solution of PBS, pH7.4. 质量控制（Quality Control） Purity: Greater than85% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. 复溶（Reconstitution） 保存（Storage） Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. 背景（Background） Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. 电泳(SDS-PAGE) FOR RESEARCH USE ONLY