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英文名称: C12orf10 Antigen (Recombinant Protein)
别 名: chromosome 12 open reading frame 10; MYG; MYG1; Gamm1; MST024; MSTP024
相关类别: 抗原
储 存: 冷冻(-20℃)
Fusion protein corresponding to a region derived from 156-376 amino acids of human C12orf10 |
技术规格
Full name: |
chromosome 12 open reading frame 10 |
Synonyms: |
MYG; MYG1; Gamm1; MST024; MSTP024 |
Swissprot: |
Q9HB07 |
Gene Accession: |
BC028904 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal ***** tissues is stable, suggesting MYG1 involvement in early developmental processes and in ***** stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility. |