英文名称： CDC23 Antigen (Recombinant Protein)
别 名： cell division cycle 23; APC8; CUT23; ANAPC8
储 存： 冷冻（-20℃）
相关类别： 抗原
|
Full name: |
cell division cycle 23 |
|
Synonyms: |
APC8; CUT23; ANAPC8 |
|
Swissprot: |
Q9UJX2 |
|
Gene Accession: |
BC017713 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
