英文名称： DECR2 Antigen (Recombinant Protein)
别 名： 2,4-dienoyl CoA reductase 2, peroxisomal; PDCR; SDR17C1
相关类别： 抗原
储 存： 冷冻（-20℃）
概 述
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Full name: |
2,4-dienoyl CoA reductase 2, peroxisomal |
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Synonyms: |
PDCR; SDR17C1 |
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Swissprot: |
Q9NUI1 |
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Gene Accession: |
BC011968 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events. |
