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别 名: teratocarcinoma-derived growth factor 1; CR; CRGF; CRIPTO
相关类别: 抗原
储 存: 冷冻(-20℃)
Fusion protein corresponding to a region derived from 31-150 amino acids of human TDGF1
Full name: |
teratocarcinoma-derived growth factor 1 |
Synonyms: |
CR; CRGF; CRIPTO |
Swissprot: |
P13385 |
Gene Accession: |
BC022393 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. |