- 入驻时间： 2020-07-28
- 联系人：王珺茹
- 电话：021-54845833
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- Email：2881498548@qq.com
英文名称： TNNI3 Antigen (Recombinant Protein)
别 名： CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
相关类别： 抗原
储 存： 冷冻（-20℃）
概 述
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Full name: |
troponin I type 3 (cardiac) |
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Synonyms: |
CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF |
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Swissprot: |
P19429 |
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Gene Accession: |
BC096165 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
