- 入驻时间： 2020-07-28
- 联系人：王珺茹
- 电话：021-54845833
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别 名： ATP-binding cassette, sub-family B (MDR/TAP), member 6; ABC; LAN; PRP; umat; ABC14; MTABC3; MCOPCB7
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Full name: |
ATP-binding cassette, sub-family B (MDR/TAP), member 6 |
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Synonyms: |
ABC; LAN; PRP; umat; ABC14; MTABC3; MCOPCB7 |
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Swissprot: |
Q9NP58 |
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Gene Accession: |
BC000559 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. |
