- 入驻时间: 2020-07-28
- 联系人:王珺茹
- 电话:021-54845833
-
联系时,请说明易展网看到的
- Email:2881498548@qq.com
概 述
Full name: |
histone deacetylase 1 |
Synonyms: |
HD1; RPD3; GON-10; RPD3L1 |
Swissprot: |
Q13547 |
Gene Accession: |
BC000301 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |