- 入驻时间： 2020-07-28
- 联系人：王珺茹
- 电话：021-54845833
-
联系时，请说明易展网看到的
- Email：2881498548@qq.com
概 述
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Full name: |
integrin subunit alpha 4 |
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Synonyms: |
IA4; CD49D |
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Swissprot: |
P13612 |
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Gene Accession: |
BC080190 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
