- 入驻时间： 2020-07-28
- 联系人：王珺茹
- 电话：021-54845833
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- Email：2881498548@qq.com
相关类别： 抗原
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Full name: |
membrane associated ring-CH-type finger 2 |
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Synonyms: |
MARCH2; RNF172; HSPC240; MARCH-II |
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Swissprot: |
Q9P0N8 |
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Gene Accession: |
BC111388 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010] |
