- 入驻时间： 2020-07-28
- 联系人：王珺茹
- 电话：021-54845833
-
联系时，请说明易展网看到的
- Email：2881498548@qq.com
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Full name: |
optineurin |
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Synonyms: |
NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP |
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Swissprot: |
Q96CV9 |
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Gene Accession: |
BC013876 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and *****-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. |
